Pegasys Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ (pre-filled syringe): 180 mcg per 0.5 mL; INJ (vial): 180 mcg per mL
Hepatitis B infection, chronic
- [180 mcg SC qwk x48wk]
- Info: see pkg insert for dose adjustments based on toxicities
Renal dosing
- [see below]
- CrCl <30: 135 mcg qwk; Info: see pkg insert for dose adjustments based on toxicities
- HD: 135 mcg qwk; no supplement after dialysis; PD: not defined; Info: see pkg insert for dose adjustments based on toxicities
Hepatic dosing
- [see below]
- Child-Pugh Class B or C or autoimmune hepatitis: contraindicated
Recommended Peds Dosing
- Dosage forms: INJ (pre-filled syringe): 180 mcg per 0.5 mL; INJ (vial): 180 mcg per mL
Hepatitis B infection, chronic
- [3 yo and older]
- Dose: 180 mcg/1.73 m^2 SC qwk x48wk; Max: 180 mcg/dose; Info: see pkg insert for dose adjustments based on toxicities
Renal dosing
- [not defined]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: consider adult renal dosing for guidance
Hepatic dosing
- [see below]
- Child-Pugh Class B or C or autoimmune hepatitis: contraindicated
SRC: NLM .