Palonosetron Dosage

Generic name: palonosetron (injection)
Brand name: Aloxi
Drug class: 5HT3 receptor antagonists

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Nausea/vomiting prevention, chemo-related

[0.25 mg IV x1]
Start: 30min before chemo

Nausea/vomiting prevention, postop

[0.075 mg IV x1]
Start: immed. before anesthesia induction

Renal dosing

[see below]
renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[no adjustment]

Recommended Peds Dosing

Dosage forms:  INJ

Nausea/vomiting prevention, chemo-related

[1 mo and older]
Dose: 20 mcg/kg/dose IV x1; Start: 30min before chemo; Max: 1.5 mg/dose

Renal dosing

[see below]
renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[no adjustment]

 

SRC: NLM .