Palonosetron Dosage
Generic name: palonosetron (injection)
Brand name: Aloxi
Drug class: 5HT3 receptor antagonists
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Nausea/vomiting prevention, chemo-related
- [0.25 mg IV x1]
- Start: 30min before chemo
Nausea/vomiting prevention, postop
- [0.075 mg IV x1]
- Start: immed. before anesthesia induction
Renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
Recommended Peds Dosing
- Dosage forms: INJ
Nausea/vomiting prevention, chemo-related
- [1 mo and older]
- Dose: 20 mcg/kg/dose IV x1; Start: 30min before chemo; Max: 1.5 mg/dose
Renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
SRC: NLM .