Generic name: palifermin
Brand name: Kepivance
Drug class: Miscellaneous uncategorized agents
Recommended Adult Dosing
Dosage forms: INJ
Mucositis prophylaxis, autologous HSCT-assoc.
- [60 mcg/kg/dose IV qd x3 consecutive days before and x3 consecutive days after myelotoxic tx for 6 total doses]
- Info: for pts w/ hematologic malignancy receiving autologous HSCT conditioning regimens predicted to result in Grade 3 or 4 mucositis; admin. 3rd dose 24-48h before start of myelotoxic tx; admin. 4th dose on day 0 after completion of hematopoietic stem cell infusion, at least 7 days after the 3rd palifermin dose
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
- [not defined]
SRC: NLM .