Palifermin Dosage

Generic name: palifermin
Brand name: Kepivance

Drug class: Miscellaneous uncategorized agents

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Mucositis prophylaxis, autologous HSCT-assoc.

[60 mcg/kg/dose IV qd x3 consecutive days before and x3 consecutive days after myelotoxic tx for 6 total doses]
Info: for pts w/ hematologic malignancy receiving autologous HSCT conditioning regimens predicted to result in Grade 3 or 4 mucositis; admin. 3rd dose 24-48h before start of myelotoxic tx; admin. 4th dose on day 0 after completion of hematopoietic stem cell infusion, at least 7 days after the 3rd palifermin dose

Renal dosing

[see below]
renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .