Ozempic Dosage

Generic name: semaglutide injection
Drug class: Incretin mimetics

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ (pen): 0.5 mg per injection, 1 mg per injection, 2 mg per injection

Diabetes mellitus, type 2

[0.5-2 mg SC qwk]

Start: 0.25 mg SC qwk x4wk, then incr. to 0.5 mg SC qwk, then may incr. to 1 mg SC qwk after at least 4wk, then may incr. to 2 mg SC qwk after at least 4wk; Max: 2 mg/wk; Info: give doses >48h apart

Cardiovascular event risk reduction – DM type 2 pts w/ estab. cardiovascular dz

[0.5-2 mg SC qwk]

Start: 0.25 mg SC qwk x4wk, then incr. to 0.5 mg SC qwk, then may incr. to 1 mg SC qwk after at least 4wk, then may incr. to 2 mg SC qwk after at least 4wk if additional glycemic control needed; Max: 2 mg/wk; Info: give doses >48h apart

Renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[no adjustment]

SRC: NLM .