Oxsoralen Dosage

Recommended Adult Dosing

Dosage forms:  CAP (soft gelatin): 10 mg

Psoriasis, severe recalcitrant disabling

[<30 kg]

Dose: 10-20 mg PO per session; Start: 10 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 20 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[30-50 kg]

Dose: 20-30 mg PO per session; Start: 20 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 30 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[51-65 kg]

Dose: 30-40 mg PO per session; Start: 30 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 40 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[66-80 kg]

Dose: 40-50 mg PO per session; Start: 40 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 50 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[81-90 kg]

Dose: 50-60 mg PO per session; Start: 50 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 60 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[91-115 kg]

Dose: 60-70 mg PO per session; Start: 60 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 70 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

[>115 kg]

Dose: 70-80 mg PO per session; Start: 70 mg PO per session, may incr. dose by 10 mg/session if inadequate response after 15 sessions; Max: 80 mg/dose; 1 dose/48h; Info: give w/ milk or food 1.5-2h prior to phototherapy

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Hepatic impairment: caution advised

SRC: NLM .