OraVerse Dosage

Generic name: phentolamine mesylate
Drug class: Miscellaneous cardiovascular agents

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ (cartridge): 0.4 mg per 1.7 mL

Dental anesthesia reversal

[0.2-0.8 mg submucosal injection x1]

Info: for reversal of local soft tissue anesthesia w/ vasoconstriction; 1 cartridge = 0.4 mg phentolamine and will reverse effects from 1 cartridge local anesthetic w/ vasoconstrictor

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ (cartridge): 0.4 mg per 1.7 mL

Dental anesthesia reversal

[6-11 yo, 15-30 kg]

Dose: 0.2 mg submucosal injection x1; Info: for reversal of local soft tissue anesthesia w/ vasoconstriction; 1 cartridge = 0.4 mg phentolamine and will reverse effects from 1 cartridge local anesthetic w/ vasoconstrictor

[6-11 yo, >30 kg]

Dose: 0.2-0.4 mg submucosal injection x1; Info: for reversal of local soft tissue anesthesia w/ vasoconstriction; 1 cartridge = 0.4 mg phentolamine and will reverse effects from 1 cartridge local anesthetic w/ vasoconstrictor

[12 yo and older, >30 kg]

Dose: 0.2-0.8 mg submucosal injection x1; Info: for reversal of local soft tissue anesthesia w/ vasoconstriction; 1 cartridge = 0.4 mg phentolamine and will reverse effects from 1 cartridge local anesthetic w/ vasoconstrictor

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .