Opzelura Dosage

Generic name: ruxolitinib
Dosage form: cream for topical use
Drug class: Topical antineoplastics

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CRM: 1.5%

Mild-moderate atopic dermatitis, short-term tx or intermittent long-term tx

[apply bid]

Max: 60 g/wk,100 g/2wk; Info: for immunocompetent pts; tx area should not exceed 20% BSA; reassess if no improvement in 8wk

Vitiligo, non-segmental

[apply bid]

Max: 60 g/wk,100 g/2wk; Info: tx area should not exceed 10% BSA; reassess if unsatisfactory response in 24wk

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  CRM: 1.5%

Mild-moderate atopic dermatitis, short-term tx or intermittent long-term tx

[12 yo and older]

Dose: apply bid; Max: 60 g/wk,100 g/2wk; Info: for immunocompetent pts; tx area should not exceed 20% BSA; reassess if no improvement in 8wk

Vitiligo, non-segmental

[12 yo and older]

Dose: apply bid; Max: 60 g/wk,100 g/2wk; Info: tx area should not exceed 10% BSA; reassess if unsatisfactory response in 24wk

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .