Olumiant Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 1 mg, 2 mg, 4 mg
Rheumatoid arthritis, mod-severe
- [2 mg PO qd]
- Info: use alone or w/ methotrexate or other non-biologic DMARDs; see pkg insert for toxicity-related dose adjustments
COVID-19
- [4 mg PO qd]
- Info: for hospitalized pts requiring supplemental oxygen, mechanical ventilation, or extracorporeal membrane oxygenation (ECMO); may give w/ remdesivir; cont. for 14 days or until hospital discharge, whichever comes first; see pkg insert for toxicity-related dose adjustments; search ‘COVID’ for additional resources including guidelines, published study summaries, and clinical trial updates
Alopecia areata, severe
- [2-4 mg PO qd]
- Info: may incr. dose to 4 mg PO qd if inadequate response or in pts w/ nearly complete or complete scalp hair loss; decr. dose to 2 mg PO qd after adequate response; see pkg insert for toxicity-related dose adjustments
Renal dosing
- [rheumatoid arthritis]
- eGFR 30-59: 1 mg qd; eGFR <30: avoid use
- HD/PD: not defined
- [COVID-19]
- eGFR 30-59: 2 mg qd; eGFR 15-29: 1 mg qd; eGFR <15: avoid use
- HD/PD: avoid use
- [alopecia areata]
- eGFR 30-59: decr. usual dose by 50%; eGFR <30: avoid use
- HD/PD: not defined
Hepatic dosing
- mild-moderate impairment: no adjustment; severe impairment: not defined
SRC: NLM .