Obizur Dosage

Generic name: Antihemophilic Factor (Recombinant [Porcine Sequence])
Drug class: Miscellaneous coagulation modifiers

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ

Acquired hemophilia A

[bleeding episode, minor-moderate]
Dose: individualize dose IV q4-12h; Start: 200 units/kg/dose IV x1; Info: adjust dose to maintain desired factor VIII level of 50-100%; dose, duration varies by site/severity of bleeding, severity of deficiency, and presence of inhibitors
[bleeding episode, major]
Dose: individualize dose IV q4-12h; Start: 200 units/kg/dose IV x1; Info: adjust dose to maintain desired factor VIII level of 100-200% until acute bleed is controlled, then maintain desired factor VIII level of 50-100%; dose, duration varies by site of bleeding, severity of deficiency, and presence of inhibitors

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .