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Nubeqa Dosage

Generic name: darolutamide
Drug classes: Antiandrogens, Hormones / antineoplastics

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 300 mg

Prostate CA

[non-metastatic castration-resistant dz]
Dose: 600 mg PO bid; Info: use w/ GnRH analog in pts w/o bilateral orchiectomy; give w/ food; do not cut/crush/chew tab
[metastatic hormone-sensitive dz]
Dose: 600 mg PO bid; Info: use w/ docetaxel; use w/ GnRH analog in pts w/o bilateral orchiectomy; give w/ food; do not cut/crush/chew tab

Renal dosing

[adjust dose amount]
eGFR 15-29: 300 mg bid; eGFR <15: not defined
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
Child-Pugh Class B: 300 mg bid; Child-Pugh Class C: not defined

 

SRC: NLM .

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