Nplate Dosage

Generic name: romiplostim
Drug class: Platelet-stimulating agents

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ

Thrombocytopenia, ITP-related

[1-10 mcg/kg/dose SC qwk]
Start: 1 mcg/kg/dose SC qwk; Max: 10 mcg/kg/wk; Info: not 1st-line agent; see pkg insert for dose adjustments based on Plt response; use lowest effective dose to achieve/maintain Plt >50,000; hold if Plt >400,000; D/C if no incr. in Plt after 4wk at max dose; use ABW to calculate dose

Hematopoietic syndrome of acute radiation syndrome

[10 mcg/kg/dose SC x1]
Start: ASAP after suspected or confirmed exposure to radiation doses >2 Gy

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .