Norvir Dosage

Generic name: ritonavir
Drug classes: Antiviral boosters, Protease inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 100 mg; PWDR: 100 mg per pkt; SOL: 80 mg per mL

HIV infection

[protease inhibitor boosting]

Dose: 100-400 mg/day PO divided qd-bid; Info: dosing varies based on concomitant PI; see other PI monographs for specific ritonavir dosing; do not cut/crush/chew tab; give w/ food

[sole protease inhibitor]

Dose: 600 mg PO bid; Start: 300 mg PO bid, incr. by 200 mg/day q2-3 days; Max: 600 mg PO bid; Info: not preferred as sole PI in regimen; do not cut/crush/chew tab; give w/ food

HIV post-exposure prophylaxis

[protease inhibitor boosting]

Dose: 100 mg PO qd; Info: part of multi-drug regimen; refer to HIV Post-Exposure Prophylaxis, Occupational and HIV Post-Exposure Prophylaxis, Nonoccupational tables; do not cut/crush/chew tab; give w/ food

Renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

mild-moderate impairment: no adjustment; severe impairment: not defined

Recommended Peds Dosing

Dosage forms:  TAB: 100 mg; PWDR: 100 mg per pkt; SOL: 80 mg per mL

HIV infection

[protease inhibitor boosting, >1 mo]

Info: dosing varies based on concomitant PI; see other PI monographs for specific ritonavir dosing; do not cut/crush/chew tab; give w/ food

HIV post-exposure prophylaxis, nonoccupational

[protease inhibitor boosting, >3 yo]

Info: dosing varies based on concomitant PI; see other PI monographs for specific ritonavir dosing; part of multi-drug regimen; refer to HIV Post-Exposure Prophylaxis, Nonoccupational table; do not cut/crush/chew tab; give w/ food

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

Hepatic dosing

mild-moderate impairment: no adjustment; severe impairment: not defined

SRC: NLM .