Nintedanib Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 100 mg, 150 mg
Idiopathic pulmonary fibrosis
- [150 mg PO q12h]
- Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
Chronic fibrosing interstitial lung dz
- [150 mg PO q12h]
- Max: 300 mg/day; Info: for pts w/ progressive phenotype; see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
Systemic sclerosis-assoc. interstitial lung dz
- [150 mg PO q12h]
- Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap
Renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A: 100 mg q12h; Child-Pugh Class B or C: avoid use
SRC: NLM .