Nimbex Dosage
Generic name: cisatracurium
Drug class: Neuromuscular blocking agents
Recommended Adult Dosing
Dosage forms: INJ
Neuromuscular blockade induction
- [150-200 mcg/kg/dose IV x1]
- Info: onset 1.5-2min, duration 55-61min (intermediate-acting); max initial bolus 20 mcg/kg/dose if neuromuscular dz; consider extended interval between dose admin. and intubation by at least 1min in elderly pts
Neuromuscular blockade maintenance
- [intermittent IV]
- Dose: 30 mcg/kg/dose IV q20min prn; Start: 40-60min after 150 mcg/kg induction dose, 50-60min after 200 mcg/kg induction dose
- [continuous IV]
- Dose: 1-2 mcg/kg/min IV; Start: 3 mcg/kg/min IV after spontaneous recovery from induction dose; Info: rates may vary widely between 0.5-10 mcg/kg/min; decr. rate 30-40% if under isoflurane or enflurane anesthesia, 50% if undergoing CABG w/ induced hypothermia
Renal dosing
- renal impairment: not defined; Info: consider extended interval between dose admin. and intubation by at least 1min if end-stage renal dz
- HD/PD: not defined
Hepatic dosing
- [not defined]
- end-stage hepatic dz: onset 1min faster vs. healthy controls
SRC: NLM .