Niaspan Dosage

Generic name: niacin (nicotinic acid)
Brand names: B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin
Drug classes: Miscellaneous antihyperlipidemic agents, Vitamins

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  ER TAB: 500 mg, 750 mg, 1000 mg

Hypercholesterolemia

[1000-2000 mg PO qhs]
Start: 500 mg PO qhs x4wk, then incr. 500 mg/day q4wk based on effect/tolerance; Max: 2000 mg/day; Info: use start regimen even when switching from other niacin products; aspirin 325 mg 30min before dose may reduce flushing; do not cut/crush/chew tab; give w/ low-fat food

Mixed dyslipidemia

[1000-2000 mg PO qhs]
Start: 500 mg PO qhs x4wk, then incr. 500 mg/day q4wk based on effect/tolerance; Max: 2000 mg/day; Info: use start regimen even when switching from other niacin products; aspirin 325 mg 30min before dose may reduce flushing; do not cut/crush/chew tab; give w/ low-fat food

Hypertriglyceridemia, type IV or V

[1000-2000 mg PO qhs]
Start: 500 mg PO qhs x4wk, then incr. 500 mg/day q4wk based on effect/tolerance; Max: 2000 mg/day; Info: use start regimen even when switching from other niacin products; aspirin 325 mg 30min before dose may reduce flushing; do not cut/crush/chew tab; give w/ low-fat food

Cardiovascular event risk reduction

[1000-2000 mg PO qhs]
Start: 500 mg PO qhs x4wk, then incr. 500 mg/day q4wk based on effect/tolerance; Max: 2000 mg/day; Info: use start regimen even when switching from other niacin products; aspirin 325 mg 30min before dose may reduce flushing; do not cut/crush/chew tab; give w/ low-fat food

CAD

[1000-2000 mg PO qhs]
Start: 500 mg PO qhs x4wk, then incr. 500 mg/day q4wk based on effect/tolerance; Max: 2000 mg/day; Info: use w/ bile acid binding resin; use start regimen even when switching from other niacin products; aspirin 325 mg 30min before dose may reduce flushing; do not cut/crush/chew tab; give w/ low-fat food

Renal dosing

renal impairment: not defined, caution advised
HD/PD: not defined

Hepatic dosing

hepatic dz hx: caution advised; unexplained elev. LFTs/active hepatic dz: contraindicated

 

SRC: NLM .