Nexavar Dosage
Generic name: sorafenib
Drug classes: Multikinase inhibitors, VEGF/VEGFR inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 200 mg
Hepatocellular CA, unresectable
- [400 mg PO bid]
- Info: give at least 1h before or 2h after food
Renal cell CA, advanced
- [400 mg PO bid]
- Info: give at least 1h before or 2h after food
Differentiated thyroid CA, refractory
- [400 mg PO bid]
- Info: for pts w/ locally recurrent or metastatic, progressive dz and who are radioactive iodine-refractory; give at least 1h before or 2h after food
Renal dosing
- renal impairment: no adjustment
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .