Neurontin Dosage

Generic name: gabapentin
Drug class: Gamma-aminobutyric acid analogs

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 100 mg, 300 mg, 400 mg; TAB: 600 mg, 800 mg; SOL: 50 mg per mL

Partial seizures

[300-1200 mg PO tid]

Start: 300 mg PO tid; Max: 3600 mg/day; Info: taper dose over >7 days to D/C

Post-herpetic neuralgia

[300-600 mg PO tid]

Start: 300 mg PO qd x1 day, then 300 mg PO bid x1 day, then 300 mg PO tid; Max: 1800 mg/day; Info: taper dose over >7 days to D/C

Neuropathic pain

[300-1200 mg PO tid]

Start: 300 mg PO qd x1 day, then 300 mg PO bid x1 day, then 300 mg PO tid; Max: 3600 mg/day; Info: taper dose over >7 days to D/C

Fibromyalgia

[400-800 mg PO tid]

Start: 300 mg PO qd x1 day, then 300 mg PO bid x1 day, then 300 mg PO tid, then titrate to effect; Max: 2400 mg/day; Info: taper dose over >7 days to D/C

Alcohol dependence

[300-600 mg PO tid]

Start: 300 mg PO qd x1 day, then 300 mg PO bid x1 day, then 300 mg PO tid; Max: 1800 mg/day; Info: taper dose over >7 days to D/C

Renal dosing

[adjust dose amount, frequency]

CrCl 30-59: 200-700 mg bid; CrCl 16-29: 200-700 mg qd; CrCl 15: 100-300 mg qd; CrCl <15: decr. dose proportionately from CrCl 15

HD: decr. dose proportionately from CrCl 15; give 125-350 mg as supplement after dialysis; PD: 300 mg q48h; supplement not defined

Hepatic dosing

[no adjustment]

SRC: NLM .