Neo-Polycin

Generic name: bacitracin, hydrocortisone, neomycin, and polymyxin B (ophthalmic)
Drug class: Ophthalmic steroids with anti-infectives

Medically reviewed by  A Ras MD.

What is Neo-Polycin used for?

Neo-Polycin is a prescription medicine that is used to treat eye infections.

Description

Neomycin and polymyxin B sulfates, bacitracin zinc and hydrocortisone acetate ophthalmic ointment is a sterile antimicrobial and anti-inflammatory ointment for ophthalmic use. Each gram contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 10,000 polymyxin B units, bacitracin zinc equivalent to 400 bacitracin units, hydrocortisone acetate 10 mg (1 %), in a white petrolatum and mineral oil base.

Bacitracin zinc is the zinc salt of bacitracin, a mixture of related cyclic polypeptides (mainly bacitracin A) produced by the growth of an organism of the licheniformis group of Bacillus subtilis var Tracy. It has a potency of not less than 40 bacitracin units per mg.

The structural formula is:

Neo-Polycin

Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). It has a potency equivalent of not less than 600 μg of neomycin standard per mg, calculated on an anhydrous basis. The structural formulae are:

Chemical Structure

Polymyxin B sulfate is the sulfate salt of polymyxin B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are:

Chemical Structure

 

Before taking Neo-Polycin, tell your doctor:

  • If you are allergic to Neo-Polycin; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have any of these health problems: Herpes, viral, or fungal infection of the eye.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Neo-Polycin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Neo-Polycin?

  • Tell all of your health care providers that you take Neo-Polycin. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how Neo-Polycin affects you.
  • Avoid wearing contacts unless told to wear them by your doctor.
  • Do not use longer than you have been told. A second infection may happen.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Neo-Polycin while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is Neo-Polycin best taken?

Use Neo-Polycin as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Use as you have been told, even if your signs get better.
  • For the eye only.
  • Wash your hands before and after use.
  • Do not touch the container tip to the eye, lid, or other skin.
  • When using, tilt your head back.
  • Pull down lower eyelid of affected eye/eyes.
  • Put a thin film of ointment into the lower eye.
  • Close eye and roll eyeball around for 1 to 2 minutes.

What do I do if I miss a dose?

  • Use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not use 2 doses or extra doses.

What are the side effects of Neo-Polycin that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Eye discharge.

What are some other side effects of Neo-Polycin?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Eye irritation.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Neo-Polycin?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Label

PACKAGE/LABEL PRINCIPAL DISPLAY PANEL – CARTON

  • Rx Only
  • NDC 0574-4144-35
  • STERILE
  • Neo-Polycin®
  • HC
  • neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone acetate
  • Ophthalmic Ointment USP
  • NET WT 3.5 g
  • (1/8 oz)

neo-polycin-carton

SRC: NLM .

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