Naprosyn Dosage

Generic name: naproxen
Brand names: Aleve, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan 375, Naprosyn
Drug class: Nonsteroidal anti-inflammatory drugs

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 500 mg; SUSP: 125 mg per 5 mL

Osteoarthritis

[250-500 mg PO q12h]

Max: 1500 mg/day x6mo; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Rheumatoid arthritis

[250-500 mg PO q12h]

Max: 1500 mg/day x6mo; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Ankylosing spondylitis

[250-500 mg PO q12h]

Max: 1500 mg/day x6mo; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Gout, acute

[250 mg PO q8h]

Start: 750 mg x1; Alt: 500 mg PO bid; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Pain, mild-moderate

[250-500 mg PO q12h]

Max: 1250 mg/day acute; 1000 mg/day maint.; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Dysmenorrhea

[250-500 mg PO q12h]

Max: 1250 mg/day; Alt: 500 mg PO x1, then 250 mg PO q6-8h; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

For anti-inflammatory uses

[250-500 mg PO q12h]

Max: 1250 mg/day acute; 1000 mg/day maint.; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Renal dosing

CrCl >60: no adjustment; CrCl 30-60: not defined, caution advised; CrCl <30: avoid use; advanced renal dz: avoid use

HD/PD: avoid use

Hepatic dosing

[not defined]

hepatic impairment: caution advised

Recommended Peds Dosing

Dosage forms:  TAB: 500 mg; SUSP: 125 mg per 5 mL

Juvenile idiopathic arthritis

[2 yo and older]

Dose: 10 mg/kg/day PO divided q12h; Max: 1000 mg/day; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Pain, mild-moderate

[2 yo and older]

Dose: 10-20 mg/kg/day PO divided q8-12h; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

*Fever

[2 yo and older]

Dose: 10-20 mg/kg/day PO divided q8-12h; Info: use lowest effective dose, shortest effective tx duration; give w/ food if GI upset occurs

Renal dosing

CrCl >60: no adjustment; CrCl 30-60: not defined, caution advised; CrCl <30: avoid use; advanced renal dz: avoid use

HD/PD: avoid use

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .