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Naloxegol Dosage

Generic name: naloxegol
Brand name: Movantik
Drug class: Peripheral opioid receptor antagonists

Medically reviewed by  A Ras MD.


Recommended Adult Dosing

Dosage forms:  TAB: 12.5 mg, 25 mg

Constipation, opioid-induced

[25 mg PO/NG qam]
Info: for pts w/ chronic non-cancer pain, incl. pain related to prior cancer or tx; may decr. dose to 12.5 mg PO/NG qam if not tolerated; give 1h before or 2h after meal

Renal dosing

[adjust dose amount]
CrCl <60: start 12.5 mg qam
HD/PD: not defined

Hepatic dosing

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined



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