Myfembree Dosage

Generic name: relugolix, estradiol and norethindrone acetate
Drug class: Sex hormone combinations

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 40 mg/1 mg/0.5 mg

Heavy menstrual bleeding, uterine fibroid-associated

[1 tab PO qd]
Start: after pregnancy excluded and w/in 7 days from onset of menses; Max: 24mo; Info: for premenopausal pts; D/C at least 4-6wk before major surgery if VTE risk

Endometriosis-associated pain, moderate-severe

[1 tab PO qd]
Start: after pregnancy excluded and w/in 7 days from onset of menses; Max: 24mo; Info: for premenopausal pts; D/C at least 4-6wk before major surgery if VTE risk

Renal dosing

CrCl >15: no adjustment; CrCl <15 or ESRD: not defined
HD/PD: not defined

Hepatic dosing

hepatic impairment/dz: contraindicated

 

SRC: NLM .