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Mycamine Dosage

Generic name: micafungin
Drug class: Echinocandins

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ

Candidemia

[100 mg IV q24h]

Candidiasis, acute disseminated

[100 mg IV q24h]

Candidal peritonitis and abscesses

[100 mg IV q24h]

Candidiasis, esophageal

[150 mg IV q24h]

Candidiasis prophylaxis, stem cell transplant

[50 mg IV q24h]

Candidiasis, oropharyngeal

[100 mg IV q24h]
Info: for fluconazole-refractory dz

Endocarditis, candidal

[150 mg IV q24h]
Info: for native valve endocarditis; not 1st-line agent; refer to IDSA and AHA guidelines

Febrile neutropenia

[100-150 mg IV q24h]
Info: for empiric tx in high-risk pts w/ persistent fever

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

[no adjustment]

Recommended Peds Dosing

Dosage forms:  INJ

Candidemia

[<4 mo]
Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
[4 mo and older]
Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

Candidiasis, acute disseminated

[<4 mo]
Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
[4 mo and older]
Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

Candidal peritonitis and abscesses

[<4 mo]
Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
[4 mo and older]
Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day

Candidiasis, esophageal

[4 mo and older, <31 kg]
Dose: 3 mg/kg/dose IV q24h
[4 mo and older, >31 kg]
Dose: 2.5 mg/kg/dose IV q24h; Max: 150 mg/day

Candidiasis prophylaxis, stem cell transplant

[4 mo and older]
Dose: 1 mg/kg/dose IV q24h; Max: 50 mg/day

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

[no adjustment]

 

 

SRC: NLM .

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