Minocin Dosage

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Infections, bacterial

[100 mg PO/IV q12h]

Start: 200 mg PO/IV x1; Max: 400 mg/24h; Alt: start 100-200 mg PO x1, then 50 mg PO q6h; Info: duration varies w/ infection type, severity

Severe acne vulgaris, adjunct tx

[50 mg PO qd-tid]

Infection, Mycobacterium marinum

[100 mg PO q12h]

Info: cont. for >3mo; clinical response varies, allow 4-6wk to assess tx

Leprosy (Hansen dz), multibacillary

[pts who cannot take clofazimine]

Dose: 100 mg PO qd x12mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 12mo in refractory cases

[pts who cannot take rifampin]

Dose: 100 mg PO qd x24mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 24mo in refractory cases

Leprosy (Hansen dz), paucibacillary

[pts who cannot take rifampin]

Dose: 100 mg PO qd x24mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 24mo in refractory cases

Renal dosing

renal impairment: decr. usual dose and/or frequency, amount not defined, max 200 mg/24h

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised

Recommended Peds Dosing

Dosage forms:  CAP: 50 mg, 75 mg, 100 mg; INJ: various

Infections, bacterial

[>8 yo]

Dose: 2 mg/kg/dose PO/IV q12h; Start: 4 mg/kg/dose PO/IV x1; Max: 400 mg/24h; Info: duration varies w/ infection type, severity

Severe acne vulgaris, adjunct tx

[12 yo and older]

Dose: 50 mg PO qd-tid

Leprosy (Hansen dz), multibacillary

[15 yo and older, pts who cannot take clofazimine]

Dose: 100 mg PO qd x12mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 12mo in refractory cases

[15 yo and older, pts who cannot take rifampin]

Dose: 100 mg PO qd x24mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 24mo in refractory cases

Leprosy (Hansen dz), paucibacillary

[15 yo and older, pts who cannot take rifampin]

Dose: 100 mg PO qd x24mo; Info: not 1st-line agent; part of multi-drug regimen; may continue tx beyond 24mo in refractory cases

Renal dosing

renal impairment: decr. usual dose and/or frequency, amount not defined, max 200 mg/24h

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .