Millipred Dosage

Generic name: prednisolone
Brand names: Flo-Pred, Millipred, Millipred DP, Orapred, Orapred ODT, Pediapred, Veripred 20
Drug class: Glucocorticoids

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 5 mg; SOL: 10 mg per 5 mL

Corticosteroid-responsive conditions

[5-60 mg/day PO divided qd-qid]

Alt: use dose pack of 5 mg tabs; start 30 mg/day, taper by 5 mg/day over 6 days or start 30 mg/day x4 days, taper by 10 mg/day q4days per pkg instructions; Info: dose, frequency varies by condition; give w/ food; taper dose gradually to D/C if high-dose or long-term use

Asthma, acute

[ED/hospital management]

Dose: 40-80 mg/day PO divided qd-bid; Info: cont. until peak flow 70% predicted; give w/ food

[outpatient burst tx]

Dose: 40-60 mg/day PO divided qd-bid x3-10 days; Info: give w/ food

Asthma, severe persistent

[7.5-60 mg PO qd-qod]

Info: give w/ food; taper dose gradually to D/C if high-dose or long-term use

Adrenal insufficiency

[4-5 mg/m^2/dose PO qd]

Info: give w/ food; taper dose gradually to D/C

Multiple sclerosis, acute exacerbation

[1250 mg PO qd x3-5 days]

Info: give w/ food

Gout, acute

[0.5 mg/kg/day PO x5-10 days]

Info: give w/ food

Alcoholic hepatitis, acute

[40 mg PO qd]

Info: give w/ food; taper dose gradually to D/C

Renal dosing

[see below]

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  TAB: 5 mg; SOL: 10 mg per 5 mL

Corticosteroid-responsive conditions

[0.14-2 mg/kg/day PO divided qd-qid]

Alt: 4-60 mg/m^2/day PO divided qd-qid; Info: dose, frequency varies by condition; give w/ food; taper dose gradually to D/C if high-dose or long-term use

Asthma, acute

[ED/hospital management]

Dose: 1-2 mg/kg/day PO divided qd-bid; Max: 60 mg/day; Info: cont. until peak flow 70% predicted; give w/ food

[outpatient burst tx]

Dose: 1-2 mg/kg/day PO divided qd-bid x3-10 days; Max: 60 mg/day; Info: give w/ food

Asthma, severe persistent

[0.25-2 mg/kg/dose PO qd-qod]

Max: 60 mg/day; Info: give w/ food; taper dose gradually to D/C if high-dose or long-term use

Adrenal insufficiency

[4-5 mg/m^2/dose PO qd]

Info: give w/ food; taper dose gradually to D/C

Nephrotic syndrome

[60 mg/m^2/day PO divided tid x4wk, then 40 mg/m^2/dose PO qod x4wk]

Info: give w/ food; taper dose gradually to D/C

Renal dosing

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

SRC: NLM .