Metolazone Dosage
Generic name: metolazone
Brand names: Zaroxolyn, Mykrox
Drug class: Thiazide diuretics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 2.5 mg, 5 mg, 10 mg
Edema, heart failure-assoc.
- [5-20 mg PO qd]
Edema, renal dz-assoc.
- [5-20 mg PO qd]
HTN
- [2.5-5 mg PO qd]
Renal dosing
- mild-moderate impairment: no adjustment; severe impairment: not defined, caution advised; anuria: contraindicated
- HD/PD: not defined, caution advised
Hepatic dosing
- hepatic coma or pre-coma: contraindicated
Recommended Peds Dosing
- Dosage forms: TAB: 2.5 mg, 5 mg, 10 mg
Edema, heart failure-assoc.
- [0.2-0.4 mg/kg/day PO divided q12-24h]
Edema, renal dz-assoc.
- [0.2-0.4 mg/kg/day PO divided q12-24h]
Renal dosing
- mild-moderate impairment: no adjustment; severe impairment: not defined, caution advised; anuria: contraindicated
- HD/PD: not defined, caution advised
Hepatic dosing
- hepatic coma or pre-coma: contraindicated
SRC: NLM .