Metolazone Dosage

Generic name: metolazone
Brand names: Zaroxolyn, Mykrox
Drug class: Thiazide diuretics

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 2.5 mg, 5 mg, 10 mg

Edema, heart failure-assoc.

[5-20 mg PO qd]

Edema, renal dz-assoc.

[5-20 mg PO qd]

HTN

[2.5-5 mg PO qd]

Renal dosing

mild-moderate impairment: no adjustment; severe impairment: not defined, caution advised; anuria: contraindicated
HD/PD: not defined, caution advised

Hepatic dosing

hepatic coma or pre-coma: contraindicated

Recommended Peds Dosing

Dosage forms:  TAB: 2.5 mg, 5 mg, 10 mg

Edema, heart failure-assoc.

[0.2-0.4 mg/kg/day PO divided q12-24h]

Edema, renal dz-assoc.

[0.2-0.4 mg/kg/day PO divided q12-24h]

Renal dosing

mild-moderate impairment: no adjustment; severe impairment: not defined, caution advised; anuria: contraindicated
HD/PD: not defined, caution advised

Hepatic dosing

hepatic coma or pre-coma: contraindicated

SRC: NLM .