Mektovi Dosage

Generic name: binimetinib
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 15 mg

Melanoma, unresectable or metastatic

[45 mg PO q12h]

Info: for pts w/ BRAF V600E or V600K mutation; use w/ encorafenib

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN and any AST: 30 mg q12h

SRC: NLM .