Marinol Dosage

Generic name: dronabinol
Brand names: Marinol, Syndros
Drug class: Miscellaneous antiemetics

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: CAP: 2.5 mg, 5 mg, 10 mg

Anorexia/weight loss, AIDS-assoc.

[2.5-10 mg PO bid]

Start: 2.5 mg PO bid, may incr. by 2.5 mg/day gradually; Max: 20 mg/day; Info: give 1h before lunch and dinner; decr. to 2.5 mg PO qpm or qhs if start dose poorly tolerated; consider starting 2.5 mg PO qpm or qhs in elderly pts; taper dose gradually to D/C if prolonged, high-dose use

Chemo-related nausea/vomiting, refractory

[5 mg/m^2/dose PO q2-4h x4-6 doses/day]

Start: 5 mg/m^2/dose PO 1-3h before chemo, may incr. by 2.5 mg/m^2; Max: 15 mg/m^2/dose; Info: give 1st dose >30 min before food, then give consistently w/ or w/o food; consider decr. to 2.5 mg qd PO qd 1-3h before chemo if poorly tolerated; consider starting 2.5 mg/m^2/dose PO qd 1-3h before chemo in elderly pts; taper dose gradually to D/C if prolonged, high-dose use

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing