Lutathera Dosage

Generic name: lutetium Lu 177 dotatate
Drug class: Therapeutic radiopharmaceuticals

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ

Restricted Distribution in US

[1-888-669-6682 or www.lutathera.com for more info]

Gastroenteropancreatic neuroendocrine tumor

[7.4 GBq IV q8wk x4 doses]
Info: for somatostatin receptor-positive dz; use w/ long-acting octreotide given 4-24h after each lutetium Lu 177 dotatate dose

*Prostate CA, metastatic castration-resistant

[7.4 GBq IV q6wk for up to 6 doses]
Info: for pts w/ progressive prostate-specific membrane antigen (PSMA)-positive dz

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

mild-mod impairment: no adjustment; severe impairment: not defined

 

SRC: NLM .