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Lumoxiti Dosage

Generic name: moxetumomab pasudotox
Drug class: Miscellaneous antineoplastics

Medically reviewed by  A Ras MD.


Recommended Adult Dosing

Dosage forms:  INJ

Hairy cell leukemia, relapsed or refractory

[0.04 mg/kg/dose IV x1 on days 1, 3, 5 of 28-day cycle]
Max: 6 cycles; Info: use ABW to calculate dose each cycle; only change dose b/w cycles if >10% change in ABW observed from ABW used at 1st dose of 1st cycle; maintain adequate hydration, consider low dose ASA on days 1-8 of each cycle

Renal dosing

CrCl >30: no adjustment; CrCl <30: avoid use
HD/PD: not defined

Hepatic dosing

bilirubin 1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN: not defined




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