Lucemyra Dosage

Generic name: lofexidine
Drug class: Antiadrenergic agents, centrally acting

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 0.18 mg

Opioid withdrawal

[3-4 tabs PO q5-6h for up to 14 days]

Start: 3 tabs PO q5-6h during peak withdrawal sx period; Max: 4 tabs/dose up to 16 tabs/day; Info: consider decr. dose to 1-2 tabs PO q5-6h in pts 65 yo and older; taper dose gradually over 2-4 days to D/C

Renal dosing

[adjust dose amount]

CrCl 30-89.9: 2 tabs q5-6h; CrCl <30: 1 tab q5-6h

HD/PD: 1 tab q5-6h; no supplement

Hepatic dosing

[adjust dose amount]

Child-Pugh Class A: 3 tabs q5-6h; Child-Pugh Class B: 2 tabs q5-6h; Child-Pugh Class C: 1 tab q5-6h

SRC: NLM .