Livmarli Dosage

Generic name: maralixibat
Dosage form: oral solution
Drug class: Miscellaneous GI agents

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  SOL: 9.5 mg per mL

Pruritus, cholestasis-assoc.

[<70 kg]

Dose: 0.38 mg/kg/dose PO qd; Start: 0.19 mg/kg/dose PO qd x1wk, then incr. to 0.38 mg/kg/dose PO qd as tolerated; Info: for pts w/ Alagille syndrome; give 30min before meal; D/C if pt progresses to portal HTN or hepatic decompensation event occurs

[>70 kg]

Dose: 28.5 mg PO qd; Start: 14.25 mg PO qd x1wk, then incr. to 28.5 mg PO qd as tolerated; Max: 28.5 mg/day; Info: for pts w/ Alagille syndrome; give 30min before meal; D/C if pt progresses to portal HTN or hepatic decompensation event occurs

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

cirrhosis: caution advised

SRC: NLM .