Levoxyl Dosage

Generic name: levothyroxine
Drug class: Thyroid drugs

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, 300 mcg

Hypothyroidism

[50-200 mcg PO qd]

Start: 1.6 mcg/kg/dose PO qd, then adjust dose by 12.5-25 mcg/day q4-6wk; Max: 300 mcg/day; Info: adjust dose based on TFTs; start 12.5-25 mcg/day, then adjust dose by 12.5-25 mcg/day q2-4wk if severe dz; start 12.5-25 mcg/day, incr. dose by 12.5 mcg/day q6-8wk in elderly pts and pts w/ cardiac dz; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach w/ full glass of water

TSH suppression

[individualize dose PO qd]

Info: for pts w/ thyrotropin-dependent well-differentiated thyroid CA; adjust dose to suppress TSH to levels based on clinical status; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach w/ full glass of water

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  TAB: 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, 300 mcg

Hypothyroidism

[<3 mo]

Dose: 10-15 mcg/kg/dose PO qd; Info: use lower dose and incr. q4-6wk if risk for cardiac failure; adjust dose based on TFTs

[3-5 mo]

Dose: 8-10 mcg/kg/dose PO qd; Info: adjust dose based on TFTs; give on empty stomach w/ water

[6-11 mo]

Dose: 6-8 mcg/kg/dose PO qd; Info: adjust dose based on TFTs; give on empty stomach w/ water

[1-5 yo]

Dose: 5-6 mcg/kg/dose PO qd; Start: 25 mcg PO qd, titrate q2-4wk if chronic or severe dz; Info: adjust dose based on TFTs; give on empty stomach w/ full glass of water

[6-12 yo]

Dose: 4-5 mcg/kg/dose PO qd; Start: 25 mcg PO qd, titrate q2-4wk if chronic or severe dz; Info: adjust dose based on TFTs; give on empty stomach w/ full glass of water

[>12 yo, growth/puberty incomplete]

Dose: 2-3 mcg/kg/dose PO qd; Start: 25 mcg PO qd, titrate q2-4wk if chronic or severe dz; Info: adjust dose based on TFTs; give on empty stomach w/ full glass of water

[>12 yo, growth/puberty complete]

Dose: 50-200 mcg PO qd; Start: 1.6 mcg/kg/dose PO qd, then adjust dose by 12.5-25 mcg/day q4-6wk; Max: 300 mcg/day; Info: adjust dose based on TFTs; start 12.5-25 mcg/day, then adjust dose by 12.5-25 mcg/day q2-4wk if severe dz; start 12.5-25 mcg/day, incr. dose by 12.5 mcg/day q6-8wk in pts w/ cardiac dz; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach w/ full glass of water

TSH suppression

[individualize dose PO qd]

Info: for pts w/ thyrotropin-dependent well-differentiated thyroid CA; adjust dose to suppress TSH to levels based on clinical status; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach w/ full glass of water

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .