Lescol Dosage

Generic name: fluvastatin
Brand names: Lescol, Lescol XL
Drug class: Statins

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  CAP: 20 mg, 40 mg

Hypercholesterolemia

[20-80 mg/day PO divided qd-bid]
Start: 20 mg PO qpm; Max: 80 mg/day; Info: start 40 mg PO qd-bid in pts w/ >25% LDL reduction goal; give qd doses in pm; divide dose bid if on 80 mg/day; do not open cap

Mixed dyslipidemia

[20-80 mg/day PO divided qd-bid]
Start: 20 mg PO qpm; Max: 80 mg/day; Info: start 40 mg PO qd-bid in pts w/ >25% LDL reduction goal; give qd doses in pm; divide dose bid if on 80 mg/day; do not open cap

Cardiovascular event risk reduction

[20-80 mg/day PO divided qd-bid]
Info: give qd doses in pm; divide dose bid if on 80 mg/day; do not open cap

Atherosclerotic cardiovascular dz

[20-80 mg/day PO divided qd-bid]
Info: give qd doses in pm; divide dose bid if on 80 mg/day; do not open cap; refer to ACC/AHA cholesterol guideline

Renal dosing

mild-mod impairment: no adjustment; severe impairment: not defined, caution advised w/ doses >40 mg/day
HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

active hepatic dz/persistent elev. LFTs: contraindicated

Recommended Peds Dosing

Dosage forms:  CAP: 20 mg, 40 mg

Heterozygous familial hypercholesterolemia

[10-16 yo, males and postmenarchal females]
Dose: 20-80 mg/day PO divided qd-bid; Start: 20 mg PO qpm, may incr. dose q6wk; Max: 80 mg/day; Info: give qd doses in pm; divide dose bid if on 80 mg/day; do not open cap

Renal dosing

[see below]
mild-mod impairment: no adjustment; severe impairment: not defined, caution advised w/ doses >40 mg/day
HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

active hepatic dz/persistent elev. LFTs: contraindicated

 

 

SRC: NLM .