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Lazanda Dosage

Generic name: fentanyl (nasal)
Drug class: Narcotic analgesics

Medically reviewed by  A Ras MD.


Recommended Adult Dosing

Dosage forms:  SPRAY: 100 mcg per actuation, 300 mcg per actuation, 400 mcg per actuation

Restricted Distribution in US

Breakthrough cancer pain, opioid-tolerant pts

[individualize dose intranasally x1 prn]
Start: 100 mcg intranasally x1; Max: 800 mcg/dose, 1 dose/episode, 4 doses/24h; Info: use lowest effective dose, shortest effective tx duration; must wait at least 2h before treating another episode; may titrate prn w/ each subsequent episode to 200 mcg dose, then 300 mcg dose, then 400 mcg dose, then 600 mcg dose, then 800 mcg dose; maint. dose reached after adequate analgesia obtained w/in 30min x2 episodes; taper dose gradually to D/C if no longer require opioid tx

Renal dosing

renal impairment: not defined, caution advised
HD/PD: not defined

Hepatic dosing

hepatic impairment: caution advised




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