Latuda Dosage

Generic name: lurasidone
Drug class: Atypical antipsychotics

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 20 mg, 40 mg, 60 mg, 80 mg, 120 mg

Schizophrenia

[40-160 mg PO qd]
Start: 40 mg PO qd; Max: 160 mg/day; Info: give w/ food containing >350 calories

Bipolar I disorder, acute depressive

[20-120 mg PO qd]
Start: 20 mg PO qd; Max: 120 mg/day; Info: for monotherapy or valproate or lithium adjunct; doses >80 mg/day rarely more effective as monotherapy; give w/ food containing >350 calories

Renal dosing

CrCl <50: start 20 mg qd, max 80 mg/day
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
Child-Pugh Class B: start 20 mg qd, max 80 mg/day; Class-Pugh Class C: start 20 mg qd, max 40 mg/day

Recommended Peds Dosing

Dosage forms:  TAB: 20 mg, 40 mg, 60 mg, 80 mg

Schizophrenia

[13-17 yo]
Dose: 40-80 mg PO qd; Start: 40 mg PO qd; Max: 80 mg/day; Info: give w/ food containing >350 calories

Bipolar I disorder, acute depressive

[10-17 yo]
Dose: 20-80 mg PO qd; Start: 20 mg PO qd x1wk; Max: 80 mg/day; Info: for monotherapy; give w/ food containing >350 calories

Renal dosing

CrCl <50: start 20 mg qd, max 80 mg/day
HD/PD: not defined

Hepatic dosing

[adjust dose amount]
Child-Pugh Class B: start 20 mg qd, max 80 mg/day; Class-Pugh Class C: start 20 mg qd, max 40 mg/day

 

SRC: NLM .