Lanreotide Dosage

Generic name: lanreotide
Brand name: Somatuline Depot
Drug class: Somatostatin and somatostatin analogs

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 60 mg per 0.2 mL, 90 mg per 0.3 mL, 120 mg per 0.5 mL

Acromegaly

[60-120 mg SC q4wk]
Start: 90 mg SC q4wk x3mo; Info: adjust dose based on GH and IGF-1 levels; may give 120 mg SC q6wk or q8wk if controlled on 60 mg or 90 mg SC q4wk

Gastroenteropancreatic neuroendocrine tumor, advanced

[120 mg SC q4wk]

Carcinoid syndrome

[120 mg SC q4wk]

Renal dosing

[acromegaly]
CrCl <60: start 60 mg q4wk; Info: caution advised if considering 120 mg q6wk or q8wk
HD/PD: not defined
[gastroenteropancreatic neuroendocrine tumor, advanced]
CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined
[carcinoid syndrome]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[acromegaly]
Child-Pugh Class B or C: start 60 mg q4wk; Info: caution advised if considering 120 mg q6wk or q8wk
[all other indications]
hepatic impairment: not defined

 

SRC: NLM .