Keppra XR Dosage

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  ER TAB: 500 mg, 750 mg

Partial seizures

[1000-3000 mg PO qd]

Start: 1000 mg PO qd, may incr. by 1000 mg/day q2wk; Max: 3000 mg/day; Info: dose adjustment may be needed during pregnancy and/or postpartum; do not cut/crush/chew tab; taper dose gradually to D/C

Renal dosing

[adjust dose amount]

CrCl 50-80: 1000-2000 mg qd; CrCl 30-50: 500-1500 mg qd; CrCl <30: 500-1000 mg qd

HD/PD: not defined; Info: consider IR form

Hepatic dosing

[no adjustment]

Recommended Peds Dosing

Dosage forms:  ER TAB: 500 mg, 750 mg

Partial seizures

[12 yo and older]

Dose: 1000-3000 mg PO qd; Start: 1000 mg PO qd, may incr. by 1000 mg/day q2wk; Max: 3000 mg/day; Info: do not cut/crush/chew tab; taper dose gradually to D/C

Renal dosing

[adjust dose amount]

CrCl 50-80: 1000-2000 mg qd; CrCl 30-50: 500-1500 mg qd; CrCl <30: 500-1000 mg qd

HD/PD: not defined; Info: consider IR form

Hepatic dosing

[no adjustment]

SRC: NLM .