Jemperli Dosage

Generic name: dostarlimab-gxly
Dosage form: injection
Drug class: Anti-PD-1 monoclonal antibodies

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Mismatch repair deficient endometrial CA, recurrent or advanced

[1000 mg IV q6wk, starting wk 13]

Start: 500 mg IV q3wk x4 doses on wk 1, 4, 7, 10; Info: for pts w/ progressive dz on or after platinum-containing chemo

Mismatch repair deficient solid tumors, recurrent or advanced

[1000 mg IV q6wk, starting wk 13]

Start: 500 mg IV q3wk x4 doses on wk 1, 4, 7, 10; Info: for pts w/ progressive dz and no alternative tx options

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

bilirubin 1-3x ULN or AST >ULN: no adjustment; bilirubin >3x ULN and any AST: not defined

SRC: NLM .