Ixazomib Dosage
Generic name: ixazomib
Brand name: Ninlaro
Dosage form: oral capsule (2.3 mg; 3 mg; 4 mg)
Drug class: Proteasome inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 2.3 mg, 3 mg, 4 mg
Multiple myeloma, relapsed or refractory
- [4 mg PO x1 on days 1, 8, 15 of 28-day cycle]
- Info: part of multi-drug chemo regimen; give at least 1h before or 2h after food; do not open cap
Renal dosing
- [adjust dose amount]
- CrCl <30: start 3 mg x1 on days 1, 8, 15 of 28-day cycle
- HD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement after dialysis; PD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement
Hepatic dosing
- [adjust dose amount]
- bilirubin >1.5x ULN: start 3 mg x1 on days 1, 8, 15 of 28-day cycle
SRC: NLM .