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Inrebic Dosage

Generic name: fedratinib
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  CAP: 100 mg

Myelofibrosis, intermediate-2 or high-risk

[400 mg PO qd]
Info: for pts w/ baseline Plt 50,000 or greater w/ primary or secondary dz

Renal dosing

[adjust dose amount]
CrCl 15-29: 200 mg qd; CrCl <15: not defined
HD/PD: not defined

Hepatic dosing

bilirubin 1-3x ULN and any AST: no adjustment; bilirubin >3x ULN and any AST: avoid use

 

SRC: NLM .

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