Inrebic Dosage
Generic name: fedratinib
Drug class: Multikinase inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 100 mg
Myelofibrosis, intermediate-2 or high-risk
- [400 mg PO qd]
- Info: for pts w/ baseline Plt 50,000 or greater w/ primary or secondary dz
Renal dosing
- [adjust dose amount]
- CrCl 15-29: 200 mg qd; CrCl <15: not defined
- HD/PD: not defined
Hepatic dosing
- bilirubin 1-3x ULN and any AST: no adjustment; bilirubin >3x ULN and any AST: avoid use
SRC: NLM .