Impoyz

Generic name: clobetasol topical
Brand names: Clobex, Clodan, Impoyz, Olux, Olux-E, Temovate, Tovet
Drug class: Topical steroids

Medically reviewed by A Ras MD.

What is Impoyz?

Impoyz Cream is a prescription corticosteroid medicine used to treat moderate to severe plaque psoriasis in people 18 years of age and older.

It is not known if Impoyz Cream is safe and effective in children under 18 years of age. Impoyz Cream is not recommended for use in children under 18 years of age.

Description

IMPOYZ (clobetasol propionate) Cream, 0.025% for topical use contains clobetasol propionate, a synthetic and fluorinated corticosteroid.

Chemically, clobetasol propionate is 21-chloro-9-fluoro-11β-hydroxy-16β-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate, and it has the following structural formula:

Clobetasol propionate has a molecular formula of C25H32ClFO5 and a molecular weight of 467. It is a white to cream-colored crystalline powder practically insoluble in water.

Each gram of IMPOYZ ™ Cream contains 0.25 mg clobetasol propionate. It is an oil-in-water emulsion intended for topical application and contains the following inactive ingredients: butylated hydroxytoluene, cetostearyl alcohol, cyclomethicone, diethylene glycol monoethyl ether, glyceryl stearate and PEG 100 stearate, isopropyl myristate, methyl paraben, propyl paraben, purified water and white wax.

Mechanism of Action

Corticosteroids play a role in cellular signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in corticosteroid responsive dermatoses is unknown. The contribution to efficacy by individual components of the vehicle has not been established.

What is the most important thing I should know about Impoyz?

Impoyz Cream is for use on the skin only. Do not get Impoyz Cream near or in your eyes, mouth, or vagina.

What should I tell my healthcare provider before using Impoyz?

Before using Impoyz Cream, tell your doctor about all of your medical conditions, including if you:

have thinning of the skin (atrophy) at the treatment site.
have a skin infection. You may need a medicine to treat the skin infection before using Impoyz Cream.
have diabetes.
have adrenal gland problems.
plan to have surgery.
liver problems.
are pregnant or plan to become pregnant. It is not known if Impoyz Cream will harm your unborn baby. If you use Impoyz Cream during pregnancy, use Impoyz Cream on the smallest area of skin and for the shortest time needed.
are breastfeeding or plan to breastfeed. It is not known if Impoyz Cream passes into breast milk. Breastfeeding women should use Impoyz Cream on the smallest area of skin and for the shortest time needed while breastfeeding. Do not apply Impoyz Cream directly to the nipple and areola to avoid contact with your baby.

Tell your doctor about all the medicines you take. including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take other corticosteroid medicines by mouth or use other products on your skin that contain corticosteroids.

Do not use other products containing a corticosteroid medicine with Impoyz Cream without talking to your doctor first.

How should I use Impoyz?

Use Impoyz Cream exactly as your doctor tells you to use it.
Your doctor should tell you how much Impoyz Cream to use and where to apply it.
Apply a thin layer of Impoyz Cream to the affected skin areas 2 times each day and rub in gently and completely.
Use Impoyz Cream for the shortest amount of time needed to treat your plaque psoriasis. Tell your doctor if your skin condition is not getting better after 2 weeks of using Impoyz. Do not use Impoyz Cream for longer than 2 weeks in a row.
Do not use Impoyz Cream on your face, scalp, underarms (armpits), groin, or areas where your skin may touch or rub together.
Do not use Impoyz Cream if thinning of the skin (atrophy) is present at the treatment site.
Do not bandage, cover, or wrap the treated skin area unless your doctor tells you to.
Wash your hand after you apply Impoyz Cream.
See your doctor regularly to check your symptoms and side effects while using Impoyz Cream.

What are the possible side effects of Impoyz?

Impoyz Cream may cause serious side effects, including:

Symptoms of a disorder where the adrenal gland does not make enough of certain hormones (adrenal insufficiency) during treatment or after stopping treatment with Impoyz Cream. Your doctor may do blood tests to check for adrenal gland problems during treatment with Impoyz Cream.
Cushing syndrome, a condition that can happen when your body is exposed to too much of the hormone cortisol. Your doctor may do tests to check for this.
High blood sugar (hyperglycemia) or diabetes mellitus that has not been diagnosed can happen with treatment. Your doctor may do tests to check for this.
Skin reactions at the treated skin site like hives, and rash. Tell your doctor if you get any skin reactions or skin infections.
Effects on growth and weight in children.

The most common side effect of Impoyz Cream includes discoloration of the treated site.

This is not the only possible side effect of Impoyz Cream.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of Impoyz

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use Impoyz Cream for a condition for which it was not prescribed. Do not give Impoyz Cream to other people even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or doctor for information about Impoyz Cream that is written for health professionals.

How should I store Impoyz?

Store Impoyz Cream between 68°F to 77°F (20°C to 25°C).
Do not freeze.
Throw away (discard) any unused Impoyz Cream after 2 weeks.

Keep Impoyz Cream and all medicines out of the reach of children.

What are the ingredients in Impoyz?

Active ingredient: clobetasol propionate

Inactive ingredients: butylated hydroxytoluene, cetostearyl alcohol, cyclomethicone, diethylene glycol monoethyl ether, glyceryl stearate and PEG 100 stearate, isopropyl myristate, methyl paraben, propyl paraben, purified water and white wax.