Hysingla ER Dosage

Generic name: hydrocodone (oral)
Drug class: Narcotic analgesics

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  ER TAB: 20 mg, 30 mg, 40 mg, 60 mg, 80 mg, 100 mg, 120 mg

Pain, severe chronic

[opioid-naive or opioid-nontolerant pts]

Dose: individualize dose PO q24h; Start: 20 mg PO q24h, may incr. by 10-20 mg/day PO q3-5 days; Info: use lowest effective dose, shortest effective tx duration; titrate slowly in pts 65 yo and older; do not cut/crush/chew/dissolve tab; doses of 80 mg/day or greater for use in opioid-tolerant pts only; taper total daily dose by no more than 10-25% q2-4wk to D/C if long-term use

[opioid-tolerant pts]

Dose: individualize dose PO q24h; Start: individualize based on current opioid intake, see pkg insert for conversion; Info: use lowest effective dose, shortest effective tx duration; titrate slowly in pts 65 yo and older; do not cut/crush/chew/dissolve tab; taper total daily dose by no more than 10-25% q2-4wk to D/C if long-term use

Renal dosing

[opioid-naive or opioid-nontolerant pts]

renal impairment: no adjustment

HD/PD: not defined

[opioid-tolerant pts]

mod-severe impairment: decr. usual start dose by 50%

HD/PD: not defined

Hepatic dosing

[opioid-naive or opioid-nontolerant pts]

hepatic impairment: no adjustment

[opioid-tolerant pts]

severe impairment: decr. usual start dose by 50%

SRC: NLM .