Hepsera Dosage

Recommended Adult Dosing

Hepatitis B infection, chronic

[10 mg PO qd]

Info: use in combo w/ lamivudine, not as adefovir monotherapy if lamivudine resistant HBV

Renal dosing

[adjust dose frequency]

CrCl 30-49: give usual dose q48h; CrCl 10-29: give usual dose q72h; CrCl <10: not defined

HD: give usual dose q7 days, on dialysis days admin. after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined

Hepatic dosing

[no adjustment]

Recommended Peds Dosing

Dosage forms:  TAB: 10 mg

Hepatitis B infection, chronic

[12 yo and older]

Dose: 10 mg PO qd; Info: use in combo w/ lamivudine, not as adefovir monotherapy if lamivudine resistant HBV

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

Hepatic dosing

[no adjustment]