Glumetza Dosage

Generic name: metformin
Brand names: Fortamet, Glucophage, Glucophage XR, Glumetza, MetFORMIN
Drug class: Non-sulfonylureas

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  ER TAB: 500 mg, 1000 mg

Diabetes mellitus, type 2

[1000-2000 mg PO qpm]

Start: 1000 mg PO qpm, incr. by 500 mg/day qwk as tolerated; Max: 2000 mg/day; Alt: 1000 mg PO bid if qd inadequate; Info: give w/ meals; do not cut/crush/chew tab; hold tx for surgery if restricting food/fluid; D/C for iodinated contrast study if eGFR 30-60, hepatic dz hx, alcoholism hx, heart failure hx, or receiving contrast intra-arterially; restart after 48h if stable renal fxn

*Polycystic ovary syndrome

[1500-2000 mg PO qpm]

Info: give w/ meals; do not cut/crush/chew tab; hold tx for surgery if restricting food/fluid; D/C for iodinated contrast study if eGFR 30-60, hepatic dz hx, alcoholism hx, heart failure hx, or receiving contrast intra-arterially; restart after 48h if stable renal fxn

Renal dosing

[diabetes mellitus, type 2]

eGFR 30-44: avoid tx initiation; eGFR <30: contraindicated; Alt: decr. usual dose by 50% if eGFR 30-44

HD/PD: avoid use

[polycystic ovary syndrome]

eGFR 30-44: avoid tx initiation; eGFR <30: contraindicated; Info: weigh risk/benefit if eGFR 30-44 during tx

HD/PD: avoid use

Hepatic dosing

hepatic impairment: avoid use

SRC: NLM .