Fomepizole Dosage

Generic name: fomepizole
Brand name: Antizol
Drug class: Antidotes

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Ethylene glycol toxicity

[15 mg/kg/dose IV q12h]

Start: 15 mg/kg/dose IV x1, then 10 mg/kg/dose IV q12h x4; Info: continue 15 mg/kg/dose IV q12h until ethylene glycol level <20 mg/dL, pt asymptomatic w/ normal pH

Methanol toxicity

[15 mg/kg/dose IV q12h]

Start: 15 mg/kg/dose IV x1, then 10 mg/kg/dose IV q12h x4; Info: continue 15 mg/kg/dose IV q12h until methanol level <20 mg/dL, pt asymptomatic w/ normal pH

Renal dosing

renal impairment: not defined; renal failure: consider hemodialysis

HD: see pkg insert; PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Ethylene glycol toxicity

[15 mg/kg/dose IV q12h]

Start: 15 mg/kg/dose IV x1, then 10 mg/kg/dose IV q12h x4; Info: continue 15 mg/kg/dose IV q12h until ethylene glycol level <20 mg/dL, pt asymptomatic w/ normal pH

Renal dosing

renal impairment: not defined; renal failure: consider hemodialysis

HD: see pkg insert; PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .