Flumadine Dosage

Recommended Adult Dosing

Dosage forms:  TAB: 100 mg; SOL: 50 mg per 5 mL

Influenza A (seasonal flu) tx

[100 mg PO bid x3-5 days]

Start: w/in 48h of sx onset; Info: not recommended per CDC and IDSA guidelines; D/C w/in 24-48h of sx resolution; give 100 mg PO qd in elderly or debilitated pts

Influenza A (seasonal flu) prophylaxis

[100 mg PO bid]

Start: prior to or immed. upon exposure; Info: not recommended per CDC and IDSA guidelines; give 100 mg PO qd in elderly or debilitated pts

Renal dosing

[adjust dose frequency]

CrCl <30: 100 mg qd

HD: 100 mg qd; no supplement after dialysis; PD: not defined

Hepatic dosing

[adjust dose frequency]

severe impairment: 100 mg qd

Recommended Peds Dosing

Dosage forms:  TAB: 100 mg; SOL: 50 mg per 5 mL

Influenza A (seasonal flu) prophylaxis

[1-9 yo]

Dose: 5 mg/kg/day PO divided qd-bid; Start: prior to or immed. upon exposure; Max: 150 mg/day; Info: not recommended per CDC and IDSA guidelines

[10 yo and older]

Dose: 100 mg PO bid; Start: prior to or immed. upon exposure; Max: 200 mg/day; Alt: 5 mg/kg/day PO divided bid; Info: not recommended per CDC and IDSA guidelines

Renal dosing

[1-9 yo]

renal impairment: not defined

HD/PD: not defined

[10 yo and older]

CrCl <30: 100 mg qd

HD: 100 mg qd; no supplement after dialysis; PD: not defined

Hepatic dosing

[1-9 yo]

hepatic impairment: not defined, consider adult hepatic dosing for guidance

[10 yo and older]

severe impairment: 100 mg qd