Fentora Dosage

Generic name: fentanyl (buccal/sublingual)
Brand names: Abstral, Fentora, Subsys
Drug class: Narcotic analgesics

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  BUC TAB: 100 mcg, 200 mcg, 400 mcg, 600 mcg, 800 mcg

Restricted Distribution in US

Special Note

[prescribing info]

Info: consider prescribing naloxone if risk of opioid overdose or accidental ingestion

[formulation clarification]

Info: transmucosal fentanyl products not bioequivalent, caution advised if switching between products; see pkg insert for conversion from other transmucosal forms; not interchangeable w/ other fentanyl products, do not substitute on a mcg to mcg basis

Breakthrough cancer pain, opioid-tolerant pts

[individualize dose buccally/SL x1 prn]

Start: 100 mcg buccally x1, may repeat x1 after 30min; Max: 4 tabs/dose; 2 doses/episode; Info: use lowest effective dose, shortest effective tx duration; must wait at least 4h before treating another episode; for initial titration incr. dose by 100 mcg/episode prn; titrate by 200 mcg if dose >400 mcg; for maint. dosing, consider incr. dose after several consecutive episodes require 2 doses; may give maint. doses SL; do not cut/chew/swallow tab; taper dose gradually to D/C if no longer require opioid tx

Renal dosing

renal impairment: not defined, caution advised

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .