Felbatol Dosage

Generic name: felbamate
Drug class: Carbamate anticonvulsants

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 400 mg, 600 mg; SUSP: 600 mg per 5 mL

Seizure disorder

[monotherapy]
Dose: 2400-3600 mg/day PO divided tid-qid; Start: 1200 mg/day PO divided tid-qid, increase by 600 mg/day q2wk if initial tx or by 1200 mg/day qwk if switching from other anti-seizure meds; Max: 3600 mg/day; Info: taper dose gradually to D/C
[adjunct tx]
Dose: 2400-3600 mg/day PO divided tid-qid; Start: 1200 mg/day PO divided tid-qid, increase by 1200 mg/day qwk; Max: 3600 mg/day; Info: taper dose gradually to D/C

Renal dosing

[adjust dose amount]
renal impairment: decrease usual dose by 50%
HD: decrease usual dose by 50%, on dialysis days admin. after dialysis; no supplement; PD: decrease usual dose by 50%; no supplement

Hepatic dosing

hepatic impairment hx: contraindicated

Recommended Peds Dosing

Dosage forms:  TAB: 400 mg, 600 mg; SUSP: 600 mg per 5 mL

Seizures, Lennox-Gastaut syndrome

[adjunct tx, 2-14 yo]
Dose: 45 mg/kg/day PO divided tid-qid; Start: 15 mg/kg/day PO divided tid-qid, incr. by 15 mg/kg/day qwk; Max: 45 mg/kg/day up to 3600 mg/day; Info: taper dose gradually to D/C

Seizure disorder

[monotherapy, 14 yo and older]
Dose: 2400-3600 mg/day PO divided tid-qid; Start: 1200 mg/day PO divided tid-qid, increase. by 600 mg/day q2wk if initial tx or by 1200 mg/day qwk if switching from other anti-seizure meds; Max: 3600 mg/day; Info: taper dose gradually to D/C
[adjunct tx, 14 yo and older]
Dose: 2400-3600 mg/day PO divided tid-qid; Start: 1200 mg/day PO divided tid-qid, increase. by 1200 mg/day qwk; Max: 3600 mg/day; Info: taper dose gradually to D/C

Renal dosing

[adjust dose amount]
renal impairment: decrease. usual dose by 50%
HD: decrease. usual dose by 50%, on dialysis days admin. after dialysis; no supplement; PD: decrease. usual dose by 50%; no supplement

Hepatic dosing

hepatic impairment hx: contraindicated

SRC: NLM .